Modelling myocardial ischaemia and reperfusion
نویسندگان
چکیده
منابع مشابه
Anaesthesia and myocardial ischaemia/reperfusion injury
Anaesthetists are confronted on a daily basis with patients with coronary artery disease, myocardial ischaemia, or both during the perioperative period. Therefore, prevention and ultimately adequate therapy of perioperative myocardial ischaemia and its consequences are the major challenges in current anaesthetic practice. This review will focus on the translation of the laboratory evidence of a...
متن کاملAnaesthesia and myocardial ischaemia/reperfusion injury.
Anaesthetists are confronted on a daily basis with patients with coronary artery disease, myocardial ischaemia, or both during the perioperative period. Therefore, prevention and ultimately adequate therapy of perioperative myocardial ischaemia and its consequences are the major challenges in current anaesthetic practice. This review will focus on the translation of the laboratory evidence of a...
متن کاملEffect of myocardial ischaemia & reperfusion on brain.
111 Very primitive man has witnessed rapid loss of life by asphyxiation and drowning, and strangulation as a means of exterminating enemies has been used since antiquity. Curville credited Ibu Sina (Avicenna Ca 954 AD) 1 as the first physician to associate clinical manifestations of asphyxiation with effect of oxygen deprivation and its detrimental effects on the brain. Francis Bacon in 1848 an...
متن کاملMouse Models for Myocardial Ischaemia/Reperfusion
The past few years have witnessed a remarkable advance in our understanding of the pathophysiology of coronary heart disease. Myocardial ischaemia usually occurs on the basis of coronary atherosclerosis. Although the functional consequences of depriving the myocardium of its blood supply have been appreciated for many years, the coronary heart disease is still the leading cause of morbidity and...
متن کاملPharmacological interventions against myocardial ischaemia and reperfusion injury
Background: Although the concept of early restoration of coronary bloodflow constitutes an important factor to reduce the injury caused by myocardial ischaemia, reperfusion in itself can aggravate the damage to myocardial tissue, a phenomenon denoted myocardial reperfusion injury. Aims: To investigate whether two different pharmacological interventions, cyclosporine A (CsA) and the novel enkeph...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Progress in Biophysics and Molecular Biology
سال: 1998
ISSN: 0079-6107
DOI: 10.1016/s0079-6107(98)00023-6